What is an effective medical treatment for severe PMS symptoms?

Selective serotonin reuptake inhibitors (SSRIs) are widely recognized as an effective treatment for severe premenstrual syndrome (PMS) symptoms, particularly when emotional symptoms such as depression, anxiety, or irritability predominate. SSRIs work by altering serotonin levels in the brain, which can help stabilize mood and reduce irritability, sadness, and anxiety typically associated with PMS.

Research supports the use of SSRIs not only for treating the emotional aspects of PMS but also for alleviating physical discomfort like bloating and breast tenderness, contributing to an overall improvement in the quality of life for individuals suffering from this condition. SSRIs can be taken continuously throughout the month or only during the luteal phase (the two weeks before menstruation) when symptoms are typically the most severe.

Other choices, while relevant to different health concerns, do not effectively address severe PMS symptoms. Thyroid hormones are indicated in cases of thyroid dysfunction but do not target the psychological and physical manifestations of PMS. Antibiotics are effective against bacterial infections but have no role in treating PMS. Insulin is essential in managing conditions like diabetes but is unrelated to the management of PMS symptoms.